NFkB Inducing Kinase NIK Antibody
Basic information
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Name
NFkB Inducing Kinase NIK Antibody
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Price
263 EUR
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Size
0.1ml
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Catalog number
bs-0074R
Detailed information
Long name
NFkB Inducing Kinase NIK Antibody
Also known as
NFkB Inducing Kinase NIK Antibody
Category
Primary Antibodies
Conjugation
Unconjugated
Target Antigen
NFkB Inducing Kinase NIK
Specificity
This is a highly specific antibody against NFkB Inducing Kinase NIK.
Modification(s)
None
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
900-947/947
Subcellular location
Cytoplasm
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIK
Gene ID number
9020
Swiss Prot
Q99558
Tested Applications
WB, IHC-P, IF(IHC-P)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity
Human, Mouse, Rat
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P1, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names
HS; NIK; HSNIK; FTDCR1B; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK; MAP3K14
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
French translation
anticorps