anti-MAPK1 Antibody
Basic information
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Name
anti-MAPK1 Antibody
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Price
180 EUR
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Size
0.05 mL
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Catalog number
48-785
Detailed information
Gene info
ERK2, a MAPK type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK2 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK2 causing dissociation of the MEK/ERK complex. A portion of the activated ERK2 pool forms dimers and translocates to the nucleus to activate nuclear proteins, such as ELK-1 and MSK1. Cytosolic ERK 2 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1.
Gene names
MAPK1, ERK, ERK-2, ERK2, MAP kinase 1, MAPK 2, MAPK2, MAP kinase isoform p42, MAPK 1, p41mapk, PRKM2, MAP kinase 2, p41, p42-MAPK, PRKM1, ERT1, p38, p40, p42MAPK, Protein tyrosine kinase ERK2
Antibodie's label
unlabelled serum
Purity
Affinity Chromatography
Ab raised in
Rabbit
Type
Polyclonal
Immunoglobulin
IgG
Antigen
MAPK1 antibody was made against a peptide mapping to the carboxy terminus of MAPK1 (Rat).
Immuno application
Western Blot, immuno-histo-chemistry, immuno precipitation
Antibody advice
MAPK1 antibody can be used in immunohistochemistry starting at 10 ug/mL, immunoprecipitation, and flow cytometry.
Suspention, pH, azide
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol, 0.1% gelatin.
Keep at
Store MAPK1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
Works with
Human, Mouse, Rat
Omim nr
119554
Ncbi nr
P28482
Vial with antibody
in solution
NCBI GENE nr
5594
GENE symbol
MAPK1
Antigene name
mitogen-activated protein kinase 1
Source
Homo sapiens
Protein nr
P28482
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps