Basic information
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Name
anti- ZAK antibody
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Price
320 EUR
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Size
2X100μg
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Catalog number
FNab09581
Detailed information
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen
sterile alpha motif and leucine zipper containing kinase AZK
Synonyms
AZK, HCCS 4, MLK related kinase, MLK7, mlklak, MLT, MLTK, MRK, ZAK
Calculated MW
55 kDa, 100 kDa
Uniprot ID
Q9NYL2
Specificity
Human, Mouse, Rat
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Image1
Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab09581( ZAK Antibody) at dilution of 1:50
Image4
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09581(ZAK antibody) at dilution of 1:1000
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Properties
If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps