JNK1/2, c-Jun N-terminal Kinase
Basic information
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Name
JNK1/2, c-Jun N-terminal Kinase
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Price
675 EUR
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Size
100 µg
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Catalog number
AS16 4011
Detailed information
Available ordering format
Liquid
Immunogen
Recombinant human c-Src expressed in E. coli. UniProt: Mouse: Q9ESN9, Human: Q9UPT6, Rat: B0VXR4
Raised in
Mouse
Clonality
Monoclonal
Clone
279Q38, IgG1
Purification
Protein A/G purified.
How to reconstitute
See included datasheet or contact our support service
Storage condition
Store at -20°C.
Verified applications
Western blotting (WB)
Connected products
anti-mouse secondary antibodies
Recommended dilutions for use
0.5-1 µg/ml (WB), optimal concentrations should be determined by serial dilutions.
Molecular weight (expected | аpparent)
see datasheet
Verified reactivity
Human, Mouse, Rat
Possible reactivity
to be determined
No reactivity
No confirmed exceptions from predicted reactivity known at the moment.
Supplementary information
Contact Gentaur support center at info@gentaur.com
References
To be added when available, antibody released in November 2016.
Scientific context
JNK is a main mitogen-activated protein kinases in mammals. Because of different mRNA splicing this protein is expressed as ten different isoforms. The most common isoforms are JNK1 and JNK2. JNK is activated by many signals in the cell such as growth factors, inflammatory cytokines, and environmental stress. The JNK pathway regulates the cell cycle, apoptotic and transcriptional responses to stress. Alternative names: Stress Activated Protein Kinase (SAPK)
Notes
This antibody binds to both JNK1 and JNK2 proteins of Mr=46 and 54 kDa.Full activation of JNK needs phosphorylation of a threonine and a tyrosine residue in the motif Thr-Pro-Tyr.
Protein number
Q9ESN9!!AIR8!!Q9UPT6!!AIR8!!B0VXR4
TAIR number
Refer to NCBI