PathwayReady™ MAP Kinase Signaling Inhibitor Panel for cell activation
Basic information
-
Name
PathwayReady™ MAP Kinase Signaling Inhibitor Panel for cell activation
-
Price
643 EUR
-
Size
7 inhibitors
-
Catalog number
K862-7
Detailed information
Description
A convenient set consisting of seven inhibitors useful for the study of MAP Kinase signaling pathway. The seven inhibitors are: 1 mg of PD 184352 (Cat. No. 1585-1), 5 mg of PD 98059 (Cat. No. 1666-5), 1 mg of SB 203580 (Cat. No. 1712-1), 25 mg of Sorafenib (Cat. No. 1594-25), 5 mg of SP 600125 (Cat. No. 1669-5), 5 mg of U0126 (Cat. No. 1668-5), and 1 mg of ZM 336372 (Cat. No. 1789-1).
Peptide sequence
N/A
CAS number
See under the individual product
Molecular weight
See under the individual product
Category
Biochemicals
Other name
MAP Kinase Signaling Inhibitor Panel, PathwayReady™
Molecular formula
See under the individual product
Physical appearance
Lyophilized solids
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥95% by HPLC
Reconstitute instructions
DMSO
Storage condition
-20°C
Shipping condition
gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell, panel
Additional description
For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.