Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1)
Basic information
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Name
Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1)
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Price
239 EUR
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Size
100 μg
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Catalog number
X2675M
Detailed information
Category
Primary Antibodies
Long description
p44 MAP Kinase (ERK) belongs to the protein kinase superfamily, the MAP kinase subfamily and contains 1 protein kinase domain It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4)._x000B__x000B_
Antibody come from
Synthetic peptide derived from the human GAPDH alpha protein.
Other description
Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
Clone
E32
Antigen-antibody binding interaction
Mouse anti MAPK3 (Mitogen-activated protein kinase 3 antibody (ERK1) Antibody
Antibody is raised in
Mouse
Antibody's reacts with
Human, Mouse
Antibody's reacts with these species
This antibody doesn't cross react with other species
Antibody's specificity
No Data Available
Application
WB, IP
Antibody's suited for
Antibody can be used for Western Blotting (1:400 dilution) and immunohistochemistry (2-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Storage
-20ºC
Relevant references
1. Nakajima, H., et al. 'GAPDH aggregate formation participates in oxidative stress-induced cell death.' J. Biol. Chem. 2009:Epub_x000B__x000B_2. Nahlik, K.W., et al. 'Modulation of GAPDH expression and cellular localization after vaccinia virus infection of human adherent monocytes.' Acta Biochim. Pol. 2003: 50(3); 667-676.
Protein number
see ncbi
Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name
Mus musculus
French translation
anticorps