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Basic information

  • Name

    NFkB Inducing Kinase NIK Antibody

  • Price

    263 EUR

  • Size

    0.1ml

  • Catalog number

    bs-0074R

Detailed information

Long name

NFkB Inducing Kinase NIK Antibody

Also known as

NFkB Inducing Kinase NIK Antibody

Category

Primary Antibodies

Conjugation

Unconjugated

Target Antigen

NFkB Inducing Kinase NIK

Specificity

This is a highly specific antibody against NFkB Inducing Kinase NIK.

Modification(s)

None

Modification site(s)

Unmodified antibody

Clonality

Polyclonal antibody

Clone number

Polyclonal antibody

Concentration

1ug per 1ul

Immunogen range

900-947/947

Subcellular location

Cytoplasm

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIK

Gene ID number

9020

Swiss Prot

Q99558

Tested Applications

WB, IHC-P, IF(IHC-P)

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Cross reactivity

Human, Mouse, Rat

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the target antigen

Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P1, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.

Purification method

This antibody was purified via Protein A.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Synonym names

HS; NIK; HSNIK; FTDCR1B; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK; MAP3K14

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Gene

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory

French translation

anticorps