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Basic information

  • Name

    anti-MAP4K2 Antibody

  • Price

    180 EUR

  • Size

    50 ug

  • Catalog number

    26-330

Detailed information

Gene info

MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

Gene names

MAP4K2, BL44, GCK, RAB8IP

Antibodie's label

unlabelled serum

Purity

Antibody is purified by peptide affinity chromatography method.

Ab raised in

Rabbit

Type

Polyclonal

Antigen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP4K2.

Immuno application

ELISA, Western Blot

Antibody advice

MAP4K2 antibody can be used for detection of MAP4K2 by ELISA at 1:312500. MAP4K2 antibody can be used for detection of MAP4K2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Suspention, pH, azide

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

Keep at

For short periods of storage (days) store at 4 grades C. For longer periods of storage, store MAP4K2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.

Works with

Human, Mouse, Rat

Omim nr

22035600

Ncbi nr

NP_004570

KDa

91 kDa

Vial with antibody

Lyophilized

Quantity per ml

1 mg/ml

NCBI GENE nr

5871

GENE symbol

MAP4K2

Antigene name

mitogen-activated protein kinase kinase kinase kinase 2

Source

Homo sapiens

Protein nr

Q12851

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps