MKK6, a MAP2K type protein kinase, is a member of the p38 MAP kinase signal transduction pathway which mediates stress induced cell cycle arrest, transcription activation and apoptosis. MKK6 can be phosphorylated by the kinases MEKK3, MEKK4, ASK1 or TAK1. Phosphorylated MKK6 activates p38 MAP kinases. At least two protein isoforms, resulting from transcript variants of the MKK6 gene, have been identified - 278 and 334 amino acids.
MAP2K6, Mapk kinase 6, MAPK/ERK kinase 6, MEK6, SAPKK3, SAPKK-3, MAP kinase kinase 6, MAPKK6, PRKMK6, MAPKK 6, MEK 6, MKK6, SAPK kinase 3, SKK3
Ab raised in
MAP2K6 antibody was made against recombinant (partial), N-Terminal region of MAP2K6 (Mouse).
Western Blot, immuno-histo-chemistry
MAP2K6 antibody can be used in ELISA starting at 1: 10000, Western Blot starting at 1: 500 - 1: 2000, and immunohistochemistry starting at 1:200.
Suspention, pH, azide
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.
Aliquot and store MAP2K6 antibody at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
Vial with antibody
NCBI GENE nr
mitogen-activated protein kinase kinase 6
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.