Need help?

+390236006593Hours: 8am-7pm M-Fri

Basic information

  • Name

    anti-MAPK1 Antibody [4C11C11C4]

  • Price

    180 EUR

  • Size

    0.05 mg

  • Catalog number

    49-771

Detailed information

Gene info

ERK2, a MAPK type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK2 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK2 causing dissociation of the MEK/ERK complex. A portion of the activated ERK2 pool forms dimers and translocates to the nucleus to activate nuclear proteins, such as ELK-1 and MSK1. Cytosolic ERK 2 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1.

Gene names

MAPK1, ERK, ERK-2, ERK2, MAP kinase 1, MAPK 2, MAPK2, MAP kinase isoform p42, MAPK 1, p41mapk, PRKM2, MAP kinase 2, p41, p42-MAPK, PRKM1, ERT1, p38, p40, p42MAPK, Protein tyrosine kinase ERK2

Antibodie's label

unlabelled serum

Purity

Affinity Chromatography

Ab raised in

Mouse

Type

Monoclonal

Monoclonal

[4C11C11C4]

Immunoglobulin

IgG2a

Antigen

MAPK1 monoclonal antibody was made against Ni-NTA purified full length recombinant ERK2 expressed in E. coli strain BL21 (DE3).

Immuno application

ELISA, Western Blot, immuno-histo-chemistry

Antibody advice

MAPK1 antibody can be used in Western Blot starting at 1:500 - 1:3000, immunohistochemistry starting at 1:400, immunoprecipitation, and immunofluorescence.

Suspention, pH, azide

PBS, 0.01% sodium azide.

Keep at

Store MAPK1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.

Works with

Human

Omim nr

119554

Ncbi nr

P28482

Vial with antibody

in solution

NCBI GENE nr

5594

GENE symbol

MAPK1

Antigene name

mitogen-activated protein kinase 1

Source

Homo sapiens

Protein nr

P28482

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps