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Basic information

  • Name

    MAPKII Kinase Inhibitor, Hsp25 Kinase Inhibitor

  • Price

    168 EUR

  • Size

    1 mg

  • Catalog number


Detailed information

Stock availabilitIn Stock

In Stock

CAS number

No Available. See included datasheet


Hsp25 Kinase Inhibitor

Molecular weight

1396,7 g/mol

Primary research fields

Cancer, Heat Shock

Other name


Product category

Small Molecules

Product type


Chemical formula




Purity pourcentage


Soluble in

Soluble in DMSO or H20

Physical appearance

White Solid

Storage recommendations


Shipping recommendations

Shipped Ambient

Safety information

Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

PubChem number

Refer to PubChem

Scientific context

The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms (1). This super family consists of stress activated protein kinases (SAPKs); extracellular signal-regulated kinases (ERKs); and p38 kinases, each of which forms a separate pathway (2). In particular, MAPKAP-kinase II (or otherwise known as MK2) is involved in inflammation, and is considered a target for therapeutic intervention for inflammation and cancer (3). MK2 is a member of the p38 MAPKinase pathway, and is activated by a variety of chemical stress inducers including hydrogen peroxide, heavy metals, anisomycin, sodium salicylate, LPS, and biological stress signals such as tumor necrosis factor, interleukin-1, ionizing and UV irradiation, hyperosmotic stress and chemotherapeutic drugs (3).


1. Pearson G. et al. (2001). Endocrine Reviews 22 (2): 153-183. 2. Fan Y., et al. (2007) Mol. Cells 23 (1): 30-38. 3. Deng et al. (2003) Cell 115: 61-70.

PubMed number

Refer to PubMed

Tested applications

To be tested

Tested reactivity

To be tested

Representative figure link

No representative figure available at this time.

Representative figure legend

No representative figure available at this time.

Warning information


Country of production


Total weight (kg)


Net weight (g)


Additional description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.