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Basic information

  • Name

    Anisomycin, p38 MAP kinase activator

  • Price

    93 EUR

  • Size

    10 mg

  • Catalog number

    SIH-266-10MG

Detailed information

Stock availabilitIn Stock

In Stock

CAS number

22862-76-6

Description

p38 MAP kinase activator

Molecular weight

265,31 g/mol

Primary research fields

Cancer, Apoptosis

Other name

(2S,3R,4R)-4-Hydroxy-2-(4-methoxybenzyl)-3-pyrrolidinyl acetate

Product category

Small Molecules

Product type

Activator

Chemical formula

C14H19NO4

Origin

Synthetic

Purity pourcentage

>98%

Soluble in

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Physical appearance

White solid

Storage recommendations

-20ÂșC

Shipping recommendations

Shipped Ambient

Safety information

Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed Hazard Phrases: H301 Precautionary Phrases: P301 + P310

PubChem number

253602

Scientific context

Anisomycin is an antibiotic which inhibits protein synthesis (1). It interferes with protein and DNA synthesis by inhibiting peptidyl transferace on the 80S ribosome system. It can activate stress-activated protein kinases, MAPkinase and other signal transduction pathways.

Bibliography

1. Grollman A.P. (1967) J Biol Chem. 242(13): 3226-3233.

Release date

8-Apr-2011

PubMed number

Refer to PubMed

Tested applications

To be tested

Tested reactivity

To be tested

Representative figure legend

Chemical structure of Anisomycin (SIH-266), a Anoikis sensitizer. CAS #: 22862-76-6. Molecular Formula: C14H19NO4 . Molecular Weight: 265.31 g/mol. Chemical structure of Anisomycin, a Anoikis sensitizer (SIH-266). CAS # 22862-76-6. Molecular Formula: C14H19NO4 .

Warning information

Non-hazardous

Country of production

Canada

Total weight (kg)

0.25

Net weight (g)

0.01