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Basic information

  • Name

    MAPK8/9 Antibody

  • Price

    320 EUR

  • Size

    0,1 mg

  • Catalog number

    PA1407

Detailed information

Target antigen

MAPK8/9

Clonality

Polyclonal antibody

Clone

Polyclonal antibody

Raised in

rabbit

Type of the antibody

IgG polyclonal antibody

Product form

freeze-dried

Reacts with species:

human

Analyses

WB,IHC-P,ICC

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human MAPK8/9(344-363aa EREHTIEEWKELIYKEVMDL), identical to the related mouse and rat sequences.

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification

Immunogen affinity purified.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Storage condtions

Keep the MAPK8/9 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Tips

The MAPK8/9 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Background

Mitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase family. The International Radiation Hybrid Mapping Consortium mapped the MAPK8 gene to chromosome 10. The single long open reading frame encodes a putative protein kinase with a predicted mass of 44.2 kD. This kinase play a key role in T cell proliferation, apoptosis and differentiation.

Related articles

1. Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ (Apr 1994). "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain". Cell 76 (6): 1025–37. doi:10.1016/0092-8674(94)90380-8. PMID 8137421. 2. Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, Davis RJ (Jul 1996). "Selective interaction of JNK protein kinase isoforms with transcription factors". EMBO J 15 (11): 2760–70. PMC 450211. PMID 8654373.

Gene Name

MAPK8

Protein Name

Mitogen-activated protein kinase 8(MAP kinase 8/MAPK 8)

Gene Full Name

Mitogen-activated Protein Kinase 8

Synonyms

JNK-46 antibody|Stress-activated protein kinase 1c antibody

Uniprot ID

P45983

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps